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Huntingtons disease (HD) is a well-characterized disorder that shares many common pathological features,such as age-de-p......
Background: The GGGGCC (G4C2) repeat expansion in the human open reading frame 72 on chromosome 9, C9orf72, is the most ......
利用CRISPR/Cas9基因敲入技术建立稳定表达FUS(fused in sarcoma)的细胞系.方法:扩增FUS 5arm序列,puro-T2A-GFP报告基因,FUS 3arm......
Mdm2 and Mdm4 are two key negative regulators of the tumor suppressor p53.Deletion of either Mdm2 or Mdm4 induces p53-de......
目的家兔是一种重要的模式动物,然而目前家兔中缺乏外源基因定点整合的相关技术。方法为了在兔胚胎成纤维细胞水平建立起成熟的H11......
Mdm2 and Mdm4 are two key negative regulators of the tumor suppressor p53.Deletion of either Mdm2 or Mdm4 induces p53-de......
【目的】研究一种在哺乳动物细胞中高效的基因敲入方法,比较带有oriP-EBNA1序列的episomal CRISPR/Cas9载体与普通CRISPR/Cas9载体......
The electrogenic Na+-HCO3– cotransporter NBCe1 encoded by SLC4A4 gene plays essential roles in the regulation of intrac......
本文阐述计算机控制多点增压发动机燃油喷射系统的硬件、软件设计。计算机控制电磁喷嘴的喷油量比惯用的车用化油器更精确，它根据发......
Background:The GGGGCC(G4C2)repeat expansion in the human open reading frame 72 on chromosome 9,C9orf72,is the most commo......
<正>下面所列4个名词代表了遗传工程操作系统中的4种不同技术方法,在目前生物医学研究领域中出现频率很高。为了使读者不致混淆其......
